Lazio host AC Milan on Saturday, 12 September 2026, with both sides meeting at 16:00 GMT in the fourth round of Serie A. Here are the expected starting line-ups for the match.
Lazio
Lazio are expected to approach the game with a strong and well-stocked squad, while Gattuso has almost all of his key players available. There are few major absences to affect his selection.
The Rome club will also have a range of options on the substitutes’ bench. Those alternatives offer experience in defence, pace and directness out wide, as well as players capable of making an impact late in the match.
That depth could prove important if the contest becomes more demanding as it progresses. With several ways to alter the shape or approach, Lazio should be able to begin the game with confidence and ambition.
Probable Lazio XI
Goalkeeper: C. Mandas
Defenders: Romano Floriani, D. Doekhi, O. Provstgaard, Nuno Tavares
Midfielders: Davide Frattesi, R. Belahyane, K. Taylor
Forwards: Gustav Isaksen, A. Pinamonti, M. Zaccagni
AC Milan
AC Milan are expected to line up in a 3-6-1 system under Ruben Amorim. The proposed formation would give the visitors three players at the back while adding extra numbers in midfield to help them control possession.
The six midfielders would be expected to provide width through the wing-backs and maintain the energy required to move up and down the pitch. In central areas, they would also be responsible for winning the ball and starting attacks.
Goncalo Ramos is set to operate as the lone forward, tasked with occupying Lazio’s defence and finishing chances created from wide positions. The system should give AC Milan greater presence in midfield, although it will require concentration and discipline to avoid leaving space on the flanks.
Probable AC Milan XI
Goalkeeper: M. Maignan
Defenders: S. Pavlovic, Koni De Winter, D. Bartesaghi
Midfielders: P. Estupinan, A. Saelemaekers, Yunus Musah, Luka Modric, Adrien Rabiot, Diego Moreira
Forward: Goncalo Ramos
The match is Lazio’s fourth-round Serie A fixture against AC Milan. Kick-off is scheduled for 16:00 GMT on Saturday, 12 September 2026.